National Academy of Sciences | Proceedings of the National Academy of Sciences of the United States of America

Journal Club

Highlighting recently published papers selected by Academy members

Journal Club: New roles found for protein key to neurotransmission

Posted on August 11, 2017 by Carolyn Beans

Scientists know many of the proteins that make neurotransmission possible, but they don’t have a handle on how all the pieces work together. “As someone who has studied the synapse for a long time, I still find it frustrating … Continue reading →

Journal Club: CRISPR elucidates genetic basis of social behavior in ants

Posted on August 10, 2017 by Viviane Callier

Drosophila has been a workhorse of genetics for roughly a century. But as a solitary insect, it hasn’t allowed researchers to investigate the genetic basis of complex social behavior in ants and bees. Now, a pair of studies published today in … Continue reading →

Journal Club: Study of volcanic gases offers new fundamental insights into the Earth’s carbon cycle

Posted on July 28, 2017 by Leslie Willoughby

To understand how the planet’s climate will evolve and has evolved over geologic time, scientists need to understand the Earth’s carbon cycle. In work recently published in Science, researchers offer new insights into that cycle, upending calculations about just how … Continue reading →

Journal Club: Ancient diet helps tell the story of Easter Island

Posted on July 21, 2017 by Carolyn Beans

Famous for its towering stone human figures, Easter Island, or Rapa Nui, has long been shrouded in mystery, with the demise of its people the subject of an intense debate. Now, new findings about what its residents ate hundreds of … Continue reading →

Journal Club: Antarctic cyanobacteria show no changes due to warming—yet

Posted on July 12, 2017 by Amber Dance

Captain Robert Scott’s Antarctic Discovery expedition took place over 100 years ago—and yet its participants recently racked up another contribution to science. Thanks to the samples of bacterial mats they collected from polar ponds—samples that were pressed, dried, and stored … Continue reading →

Journal Club: Insights from 3-D images defy assumptions about how plant cells communicate

Posted on June 23, 2017 by Carolyn Beans

When plant cells communicate, plasmodesmata serve as crucial conduits. These channels cross cell walls, linking one cell to its neighbor. If a plant needs to grow larger or fight off a pathogen, molecular signals pass through plasmodesmata to keep cells … Continue reading →

Categories: Cell Biology | Journal Club | Plant Biology | Tagged Arabidopsis, cell communication, electron microscopy, plant cell, plasmodesmata | Leave a comment

Journal Club: Mutation helps Zika virus evolve to more easily infect mosquitoes, spread infection

Posted on June 16, 2017 by Carolyn Beans

Scientists discovered the Zika virus over half a century ago. But it wasn’t until recent outbreaks in French Polynesia and South America that the mosquito-borne virus, now associated with Guillain-Barre syndrome in adults and microcephaly in newborn babies, reached epidemic … Continue reading →

Journal Club: Engineered enzyme could streamline synthesis of nitrogen containing compounds

Posted on June 15, 2017 by Jessica P. Johnson

Researchers have re-engineered a bacterial enzyme to transform abundant alkanes into industrially important nitrogen-containing compounds that can be used to synthesize pharmaceuticals. In principle, the enzyme, now called P411CHA, could help streamline some methods for creating synthetic molecules, which often … Continue reading →

Journal Club: Macrophages help regenerate ear parts in spiny mice

Posted on June 10, 2017 by Jyoti Madhusoodanan

Salamander tails and fish fins are oft-cited examples of animals’ ability to regenerate a lost limb or organ. But one mammal—the African spiny mouse—has also emerged as a model of regenerative abilities. In a recent study, Ashley Seifert of the University … Continue reading →

Journal Club: Metal-based compound shows rare specificity in early tests of its cancer-fighting capabilities

Posted on June 6, 2017 by Charles Choi

Many drugs used to fight cancer are based on metals. But such organometallic agents are generally thought to have low specificity for potential targets in cells, raising concerns that they may inflict collateral damage on healthy cells. Now scientists have … Continue reading →

Categories: Biochemistry | Journal Club | Medical Sciences | Tagged cancer, microtubules, organometallic compound, plectin, proteomics, ruthenium, tumors | Leave a comment