Journal Club

Highlighting recently published papers selected by Academy members

Category Archives: Cell Biology

Journal Club: Microvesicles facilitate crucial signals in developing embryos

Early in mammal development, tiny vesicles provide key communication between the cells that will become the fetus and those destined to form the placenta, researchers have found. The message the microvesicles are imparting: It’s time to implant into the wall … Continue reading

Categories: Cell Biology | Tagged , , , | Leave a comment

Journal Club: Rule-breaking microbe lacks mitochondria

Mitochondria, organelles central to cellular metabolism and energy production, are typically a hallmark of the eukaryotic cells that make up plants, animals, fungi, and many other organisms. Now scientists report the first known example of a eukaryotic organism that lacks … Continue reading

Categories: Biochemistry | Cell Biology | Journal Club | Tagged , , | Leave a comment

Journal Club: Tasmanian devils hit with another contagious cancer

Cancers aren’t usually contagious, but a tiny number of them can spread when diseased cells move from one animal to another. One such cancer, an aggressive facial tumor, has wiped out large numbers of Tasmanian devils in Australia over the … Continue reading

Categories: Cell Biology | Ecology | Genetics | Tagged , , | Leave a comment

Journal Club: T-cells transform, defying expectations and suggesting a new therapeutic avenue

Inflammation can help the human body fight off infections. If left unchecked, it can also lead to a variety of inflammatory disorders, such as gout and lupus. Now scientists find that in mice, a kind of immune cell that normally … Continue reading

Categories: Cell Biology | Genetics | Immunology | Journal Club | Tagged , , , , | Leave a comment

Journal Club: A new take on why tumors develop drug resistance

Cancer’s notorious resistance to therapy is often explained as the result of natural selection of newly mutating cells. Cancer-killing drugs wipe out nearly all of a tumor’s cells, but random mutations may allow for drug resistance in some cells, and … Continue reading

Categories: Cell Biology | Evolution | Journal Club | Medical Sciences | Tagged , , , , , , | Leave a comment

Journal Club: Newly found tiny peptides may have a big role

Tiny proteins known as micropeptides can play key roles in developmental biology. These molecules are encoded by equally little bits of DNA known as short or small open reading frames that often escape detection amidst an extraordinary number of meaningless … Continue reading

Categories: Biochemistry | Cell Biology | Genetics | Journal Club | Medical Sciences | Tagged , , | Leave a comment

Journal Club: Experimental technique uncovers new cell types in the brain

The brain is the most complex organ in the body, and presents countless mysteries – including the very nature of all the cells contribute to its function. By using single-cell RNA sequencing to map the genetic activity in more than … Continue reading

Categories: Cell Biology | Journal Club | Neuroscience | Tagged , , , | Leave a comment

The secrets of sticky starfish feet

Animals like mussels and barnacles produce strong adhesives that don’t dissolve in water. One reason this property has drawn the interest of scientists because of the potential to produce commercial products that mimic these sticky underwater properties. Yet the starfish, … Continue reading

Categories: Cell Biology | Leave a comment

Researchers flesh out new model describing tissue mechanics

Enough tension will do anything in. Cells grown in a constrained environment, in a matrix or on a platform, have a bad habit of breaking due to their own strength. Though frustrating for those working in regenerative medicine, which seeks … Continue reading

Categories: Cell Biology | Engineering | Tagged , , | Leave a comment

Serotonin alters body’s insulin response in pregnancy

While most people have to worry about eating just enough to keep their own body functioning, a pregnant woman has an extra job: keeping nutrients flowing toward her baby. In a new PNAS Early Edition paper, researchers have discovered one … Continue reading

Categories: Cell Biology | Leave a comment