Researchers have re-engineered a bacterial enzyme to transform abundant alkanes into industrially important nitrogen-containing compounds that can be used to synthesize pharmaceuticals. In principle, the enzyme, now called P411CHA, could help streamline some methods for creating synthetic molecules, which often … Continue reading
Journal Club
Highlighting recent, timely papers selected by Academy member labs
Tag Archives: drugs
Journal Club: Engineered enzyme could streamline synthesis of nitrogen containing compounds
Categories: Chemistry | Environmental Sciences | Journal Club | Sustainability Science
Tagged benzylamine, cytochrome P450, drugs, enzyme, green chemistry
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Journal Club: Layer-cake chemistry offers up a cheap way to perform chemical tests
Sana Jahanshahi-Anbuhi started her study with a trip to the supermarket to buy Listerine breath strips, the sort that melt on your tongue in seconds. But the chemical engineering postdoc at McMaster University in Hamilton, Canada wasn’t worried about bad … Continue reading
Categories: Biochemistry | Chemistry | Environmental Sciences | Journal Club | Microbiology | Pharmacology
Tagged chemical test, drugs, E. coli, genome sequencing, lab on a chip
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Journal Club: A new take on why tumors develop drug resistance
Cancer’s notorious resistance to therapy is often explained as the result of natural selection of newly mutating cells. Cancer-killing drugs wipe out nearly all of a tumor’s cells, but random mutations may allow for drug resistance in some cells, and … Continue reading
Categories: Cell Biology | Evolution | Journal Club | Medical Sciences
Tagged cancer, drugs, natural selection, phenotypic plasticity, stem cells, therapy, tumor
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