Neurons message each other with the help of excitatory or inhibitory neurotransmitters. But to actually deliver those messages, the neurotransmitters must dock with protein receptors embedded in the cell membranes of adjacent neurons. Of particular interest in the human brain … Continue reading
Journal Club
Highlighting recently published papers selected by Academy members
Tag Archives: GABA receptor
Journal Club: Newly solved structure of a GABA receptor could offer drug design insights
Categories: Journal Club | Neuroscience | Pharmacology
Tagged cryo-EM, depression, epilepsy, GABA receptor, ligand, neurotransmitter, X-ray crystallography
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Journal Club: New clues in the mystery of the mechanism of general anesthetics
Anesthetics have been used in surgery since the mid-1800s, but their exact mechanisms of action continue to be the subject of intense investigation. Past studies have suggested they block neurotransmitter receptors postsynaptically. Now a new study, published January 9 in … Continue reading
Categories: Biochemistry | Journal Club | Medical Sciences | Neuroscience | Pharmacology
Tagged anesthetics, GABA receptor, neurotransmitter, SNARE, syntaxin
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