Journal Club

Highlighting recently published papers selected by Academy members

Tag Archives: neurons

Journal Club: Microglial protein trafficking could play a role in neurodegenerative disorders

Neurodegenerative conditions such as Alzheimer’s disease (AD) or Parkinson’s are associated with a build-up of insoluble, toxic forms of proteins such as amyloid or tau in the brain. Normally, intracellular protein complexes known as retromers help with recycling and trafficking … Continue reading

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Journal Club: Fruit flies’ internal circadian clocks continually check the temperature

As a fruit fly sails from sunshine into a patch of shade, its temperature drops by 10 degrees F or so. Immediately, certain neurons in its brain spring into action, telling the fly’s circadian clock about the temperature change. By … Continue reading

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Journal Club: Illuminating the neurons that help fruit fly larvae escape danger

Disturb fruit fly larvae with sharp jabs or intense heat and they’ll respond the same way every time. “They always roll two or three times, and then stop rolling and land away from the noxious thing,” says neuroscientist Kazuo Emoto … Continue reading

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Journal Club: Tracking memories in fruit fly brains

Memories help animals make predictions. A honeybee may remember that the smell of orange blossoms means nectar is nearby. But sometimes memories require updating. “If you know that your fridge is a good source of food, and you go to … Continue reading

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Journal Club: Food first—Safety, friends, and water can come later

Suppose you’re hungry, but also cold. Your dog is barking at someone at the door, and you see your spouse heading toward the fridge—you wonder if he will take the last of the leftover pizza. With many competing factors vying … Continue reading

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Journal Club: “Sandman” molecule controls when fruit flies wake up

Sleep cuts people off from the outside world, which entails considerable risks and costs that scientists reason must be counterbalanced by a vital but enigmatic benefit. Now scientists have discovered what makes a switch flip in the brains of fruit … Continue reading

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Journal Club: Experimental technique uncovers new cell types in the brain

The brain is the most complex organ in the body, and presents countless mysteries – including the very nature of all the cells contribute to its function. By using single-cell RNA sequencing to map the genetic activity in more than … Continue reading

Categories: Cell Biology | Journal Club | Neuroscience | Tagged , , , | Leave a comment