Fatal neurodegenerative diseases including Alzheimer’s, Parkinson’s, and amyotrophic lateral sclerosis (ALS) begin as tiny pockets of misfolded proteins that evade the body’s normal detritus-removal systems. They spread throughout the brain and clog neural pathways. But exactly how these proteins propagate … Continue reading
Journal Club
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Tag Archives: protein folding
Journal Club: Shark blood compound offers up novel mechanism for stabilizing folded proteins
Sharks and other sea life often maintain high levels of trimethylamine N-oxide (TMAO) in their blood, a compound vital to their surviving in the saline environment. TMAO helps maintain an osmotic balance between body tissues and sea water to prevent … Continue reading
Categories: Biochemistry | Chemistry | Journal Club
Tagged blood, elastin-like polypeptide, model, osmolyte, protein folding, sharks, simulation, trimethylamine N-oxide
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