Cancer cells tend to turn their extracellular environment acidic, thus helping these rogue cells thrive while creating a hostile environment for normal ones. Acidosis promotes tumor growth, metastasis and drug resistance, while helping tumor cells evade the immune system. But … Continue reading
Journal Club
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Tag Archives: tumor
Journal Club: A new take on why tumors develop drug resistance
Cancer’s notorious resistance to therapy is often explained as the result of natural selection of newly mutating cells. Cancer-killing drugs wipe out nearly all of a tumor’s cells, but random mutations may allow for drug resistance in some cells, and … Continue reading
Categories: Cell Biology | Evolution | Journal Club | Medical Sciences
Tagged cancer, drugs, natural selection, phenotypic plasticity, stem cells, therapy, tumor
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