Journal Club

Highlighting recently published papers selected by Academy members

Tag Archives: tumor

Journal Club: Cellular context determines whether factor promotes or tamps down cancer

Some cellular factors have an impressive multitude of roles. One prime example is LKB1 (Liver Kinase B1). It controls both cell metabolism and cell polarity, telling cells which end is which. It also appears to act as both a tumor … Continue reading

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Journal Club: 3-D Microtumor Model Offers New Insights into Tumor Progression

Most cancer-related deaths are caused by metastasis, as cancers spreads to sites throughout the body. Breast cancer metastasis is strongly associated with tumor size, and scientists want to better understand how these factors are linked. Now researchers have developed a … Continue reading

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Journal Club: A new take on why tumors develop drug resistance

Cancer’s notorious resistance to therapy is often explained as the result of natural selection of newly mutating cells. Cancer-killing drugs wipe out nearly all of a tumor’s cells, but random mutations may allow for drug resistance in some cells, and … Continue reading

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