Journal Club

Highlighting recent, timely papers selected by Academy member labs

Category Archives: Engineering

Hydrogel uses biology and light to release proteins on demand, advancing hopes for synthetic tissues

A wiggly cylinder of protein, hydrogel, and human cells, about the size of a wristwatch battery, could one day serve as a building block for synthetic tissues. The implications could be big for biological research and even organ transplants, according … Continue reading

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Journal Club: In big advance for lab-grown organs, 3-D printing better replicates tissue complexity

The lung is a feathery web of blood vessels and air sacs that branch closely together, but never touch. They’re nestled near enough that oxygen can diffuse into the bloodstream, but far enough that blood and air flow through separate … Continue reading

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Journal Club: Diagnosing disease with smartphone cameras

Bioengineers at the University of Washington have devised a way to use smartphone cameras for imaging diagnostics, paving the way to test for afflictions such as influenza and sexually transmitted infections without costly equipment. The technique, presented this month in Analytical … Continue reading

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Journal Club: Ancient fish moving to land used their tails as crutches

The evolution from fish living in water to vertebrates living on land was one of the most pivotal moments in the history of the animal kingdom. Now scientists using robot fish suggest that these ancient pioneers may have used their … Continue reading

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Diagnosing asthma from a single drop of blood

Asthma affects more than 300 million people worldwide, and over the past 30 years, the prevalence of asthma has risen significantly in many populations. Unfortunately, asthma is notoriously difficult to diagnose. Now scientists have developed a handheld device that could … Continue reading

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Printing living cells with “woodblocks”

The inkjet printer technology often seen in offices is now finding use in research that uses suspensions of living cells as their ink to explore ways to manufacture complex tissues and organs. However, inkjet-based cell printing leaves many cells damaged … Continue reading

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Engineered nanomaterials grow smaller and stronger

Materials scientists have a few options for making lighter, yet stronger materials: improve the strength, lower the density, or both. But at a certain point, it’s tough to get much much stronger without added bulk. Jens Bauer and his colleagues … Continue reading

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Researchers flesh out new model describing tissue mechanics

Enough tension will do anything in. Cells grown in a constrained environment, in a matrix or on a platform, have a bad habit of breaking due to their own strength. Though frustrating for those working in regenerative medicine, which seeks … Continue reading

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Smaller nano-channel weighs with attogram precision

The mass of nanoparticles as small as 10 nanometers in diameter can be determined with attogram precision by measuring the oscillations of a cantilevered nanobeam supporting the particles, researchers report in the Proceedings of the National Academy of Sciences. Furthermore, … Continue reading

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Binding protein to white blood cells kills metastasizing cancer cells

A common protein that kills cancer cells in the bloodstream works shows improved efficiency when bound to the surface of white blood cells, scientists report in the Proceedings of the National Academy of Sciences. Cancer cells that migrate from one … Continue reading

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3D culturing of human stem cells

Human pluripotent stem cells are capable of becoming any tissue in the body, making them promising for numerous medical applications, all of which require large numbers of cells of high quality. Now scientists report a simple, efficient, scalable 3D system … Continue reading

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