Journal Club

Highlighting recently published papers selected by Academy members

Tag Archives: Amyotrophic lateral sclerosis

Journal Club: Simple model reproduces patterns of toxic protein buildup across multiple neurodegenerative diseases

Fatal neurodegenerative diseases including Alzheimer’s, Parkinson’s, and amyotrophic lateral sclerosis (ALS) begin as tiny pockets of misfolded proteins that evade the body’s normal detritus-removal systems. They spread throughout the brain and clog neural pathways. But exactly how these proteins propagate … Continue reading

Categories: Cell Biology | Journal Club | Mathematics | Neuroscience | Physics | Uncategorized | Tagged , , , , , , | Leave a comment

Journal Club: ATP could help proteins dissolve in cells, prompting a rethink about its function and evolution

Adenosine triphosphate (ATP) is widely considered biology’s “energy currency”. A crucial player in cell function, it stores and releases energy for enzymatic reactions in its phosphate bonds. But cells typically hoard amounts of ATP several hundred-fold higher than that needed … Continue reading

Categories: Biochemistry | Cell Biology | Journal Club | Tagged , , , | 1 Comment