Tag Archives: ion channel

New protein structure reveals hotspot for cystic fibrosis drug binding

Posted on June 29, 2019 by Amber Dance

The newly revealed structure of a cystic fibrosis drug, captured in tandem with its target channel protein, could help scientists design better medications for the condition. Cystic fibrosis results from mutations in the gene for the cystic fibrosis transmembrane … Continue reading →

Journal Club: Newly discovered ion channel gene promises disease insights

Posted on May 3, 2019 by Amy McDermott

The molecular identity and precise function of a commonly expressed cell-membrane chloride channel has long been a mystery. A recent study in Science uncovers the gene responsible for the channel, potentially shedding light on its role in the body. Researchers … Continue reading →

Journal Club: Key protein family helps govern sense of touch in both plants and animals

Posted on November 16, 2018 by Amber Dance

Compared to their knowledge of other senses, scientists know relatively little about how cells sense touch. A newly confirmed family of mechanosensors, comprising more than a dozen members and present in both plants and animals, is an important step toward … Continue reading →

Categories: Cell Biology | Journal Club | Neuroscience | Tagged cell membrane, cell wall, ion channel, mechanosensor, OSCA protein, sense of touch, TMEM63 protein | Leave a comment

Journal Club: Proprioceptive neurons offer new insights into a “sixth sense”

Posted on June 25, 2018 by Jessica P. Johnson

Proprioception allows people to know the position of parts of the body without seeing them, enabling us to touch type, walk in the dark without falling over, or drive a car while looking at the road. Defects in this sensory … Continue reading →