Genes that code for proteins make up only about 2% of the human genome. Many researchers once dismissed the other 98% of the genome as “junk DNA,” but geneticists now know these noncoding regions help to regulate the activity of … Continue reading
Journal Club
Highlighting recent, timely papers selected by Academy member labs
Tag Archives: lncRNA
Noncoding DNA shown to underlie function, cause limb malformations
Categories: Biochemistry | Genetics | Journal Club
Tagged CRISPR, EN1, gene, junk DNA, lncRNA
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Journal Club: Mutations in non-coding gene signal risk of celiac disease
Researchers struggling to find genes linked to celiac disease may have been looking in the wrong place. Recent findings have uncovered a gene that appears to amplify risk for the common autoimmune disorder by spelling out not a protein, but … Continue reading
Categories: Applied Biological Sciences | Genetics | Journal Club
Tagged celiac disease, lncRNA
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Journal Club: Newly found tiny peptides may have a big role
Tiny proteins known as micropeptides can play key roles in developmental biology. These molecules are encoded by equally little bits of DNA known as short or small open reading frames that often escape detection amidst an extraordinary number of meaningless … Continue reading
Categories: Biochemistry | Cell Biology | Genetics | Journal Club | Medical Sciences
Tagged lncRNA, micropeptide, non-coding RNA
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