Journal Club

Highlighting recently published papers selected by Academy members

Tag Archives: protein folding

Journal Club: Simple model reproduces patterns of toxic protein buildup across multiple neurodegenerative diseases

Fatal neurodegenerative diseases including Alzheimer’s, Parkinson’s, and amyotrophic lateral sclerosis (ALS) begin as tiny pockets of misfolded proteins that evade the body’s normal detritus-removal systems. They spread throughout the brain and clog neural pathways. But exactly how these proteins propagate … Continue reading

Categories: Cell Biology | Journal Club | Mathematics | Neuroscience | Physics | Uncategorized | Tagged , , , , , , | Leave a comment

Journal Club: Shark blood compound offers up novel mechanism for stabilizing folded proteins

Sharks and other sea life often maintain high levels of trimethylamine N-oxide (TMAO) in their blood, a compound vital to their surviving in the saline environment. TMAO helps maintain an osmotic balance between body tissues and sea water to prevent … Continue reading

Categories: Biochemistry | Chemistry | Journal Club | Tagged , , , , , , , | Leave a comment